Tropomyosin 1 (Alpha) (TPM1) (Middle Region) Peptide
TPM1
适用: 人
宿主: 合成
BP, WB
Quick Overview for Tropomyosin 1 (Alpha) (TPM1) (Middle Region) Peptide (ABIN985414)
抗原
Tropomyosin (TPM1)
(Tropomyosin 1 (Alpha) (TPM1))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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产品特性
- This is a synthetic peptide designed for use in combination with anti-TPM1 antibody (Catalog #: ARP41443_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))
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背景
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TPM1 is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy.
Alias Symbols: C15orf13, HTM-alpha, TMSA, CMH3, CMD1Y
Protein Interaction Partner: ACTB,C19orf50,EPB41,JUN,PKD2,S100A2,TMOD2,TNNT1,TNNT2,TPM2,C19orf50,CNN1,TNNT1,TNNT2,TPM1,TPM2
Protein Size: 245 -
分子量
- 28 kDa
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基因ID
- 7168
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NCBI登录号
- NM_001018008, NP_001018008
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UniProt
- Q7Z6L8
抗原
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